In 1960, producer/director William Castle cast Hamilton as a housekeeper in his 13 Ghosts horror film, in which 12-year-old lead Charles Herbert's character taunts her about being a witch, including the final scene, in which she is holding a broom in her hand. Mankiewicz's People Will Talk (1951) as Sarah Pickett.
Opposite Bud Abbott and Lou Costello, she played a heavily made-up witch in Comin' Round the Mountain, where her character and Costello go toe-to-toe with voodoo dolls made of each other. She appeared regularly in supporting roles in films until the early 1950s and sporadically thereafter. Her crisp voice with rapid but clear enunciation was another trademark. Later in the decade, she was in a little-known film noir, titled Bungalow 13 (1948), in which she again costarred opposite Cromwell. Hamilton costarred opposite Buster Keaton and Richard Cromwell in a 1940s spoof of the long-running local melodrama The Drunkard, titled The Villain Still Pursued Her. She strove to work as much as possible to support herself and her son she never put herself under contract to any one studio and priced her services at $1,000 ($18,000 with inflation ) a week. Fields, 1940), and The Sin of Harold Diddlebock (with Harold Lloyd, 1947). She went on to appear in These Three (1936), Saratoga, You Only Live Once, When's Your Birthday?, Nothing Sacred (all 1937), The Adventures of Tom Sawyer (1938), My Little Chickadee (with W. Hamilton made her screen debut in 1933 in Another Language. Before she turned to acting exclusively, her parents insisted she attend Wheelock College in Boston, which she did, later becoming a kindergarten teacher. Brooks Theater at the Cleveland Play House.
Hamilton made her debut as a "professional entertainer" on December 9, 1929, in a "program of 'heart rending songs'" in the Charles S. Hamilton also practiced her craft doing children's theater while she was a Junior League of Cleveland member. Drawn to the theater at an early age, Hamilton made her amateur stage debut in 1923. She attended Hathaway Brown School while the school was at 1945 East 93rd Street in Cleveland. Hamilton and his wife, Mary Jane (née Adams known by her nickname, Jennie). Hamilton was born in Cleveland, the youngest of four children of Walter J.